Add the unique benefits of hyaluronic acid
to your surgical toolbox.
Hyaluronic acid (HA) is a major biochemical difference between fetal and adult wound environments. Hyalomatrix puts HA’s innate tissue regeneration properties in your skilled hands, helping you bring new hope to patients and their families. It features esterified HYAFF, an exceptionally long-lasting form of HA. HYAFF delivers HA to the wound bed in a prolonged manner, facilitating each stage of the healing process.1-5
Mechanisms of action
The HYAFF technology behind Hyalomatrix is based on hyaluronic acid rather than collagen, making it unique among skin substitutes.
HA binds 1,000 times its weight in water. This helps facilitate cellular migration and creates water-rich space that helps organize collagen, which is key to reducing scar tissue formation.10, 11
HA facilitates an increase in pro-inflammatory cytokines, activating and recruiting native cells—including endothelial cells and fibroblasts.12,13
Presented as fibers, the HYAFF serves as a scaffold, giving the patient’s native cells a place to live, thrive and rebuild tissue. Without cross-linking, the open scaffold allows for cellular infiltration and capillary growth.6