Mechanisms of action
Surfactanct-based autolytic debridement
PluroGel is a stable, viscous gel composed of a high concentration of surfactant micelles. Each micelle has a hydrophilic outer surface that softens and loosens wound debris, and a hydrophobic inner core that traps debris. The micelles link to form a matrix that continually expands and contracts. This creates a cleansing/rinsing action that disrupts the surface tension holding slough and necrotic tissue in place.
Inverse thermodynamic properties enable PluroGel to thicken in a warm environment and remain on the wound bed, allowing constant contact with debris. Because PluroGel is 100 percent water soluble, debris is removed by rinsing with saline or cleanser at dressing change.